The effects of sildenafil on rectal sensitivity and tone in patients ...

Background: Visceral tone supposedly affects gut sensitivity in irritable bowel syndrome (IBS). Sildenafil increases nitric oxide and influences visceral compliance. Aim: To evaluate the effects of sildenafil tone inhibition on rectal sensitivity. Methods: Eight controls and 21 IBS patients (Rome II) were enrolled in a double-blind study, after dosing with placebo or sildenafil (50 mg p.o.).

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okay so I crushed 25mg viagra and put it into a veggie capsule. After insertion, waited about 30 mins, didn't feel anything. After an hour, I took a shit and the capsule was in there (opened), but the crushed viagra was in it still. So there was no absorption! I guess the veggie capsules don't dissolve, but wondering what should i put the ...

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