Past, present, and future: a 7-year update of Viagra (sildenafil ...

Viagra (sildenafil citrate), the first-in-class phosphodiesterase type 5 (PDE5) inhibitor, was introduced in 1998 for the treatment of ED. In the 7 years since its market launch, more than 750,000 physicians have prescribed sildenafil to more than 23 million men, helping establish an excellent safety and efficacy record.

Viagra Prescriptions: The End of Sex Was Predicted, But Didn't ... - TIME

After the FDA approved Viagra on this day, March 27, in 1998, sales of the drug rose quickly — pumped by an early rush that yielded at least 10,000 scripts a day, per a TIME cover story about ...

Achieving treatment optimization with sildenafil citrate (Viagra) in ...

Since its approval in 1998, sildenafil citrate (Viagra) has been shown to be efficacious in >100 clinical trials involving >8000 men with erectile dysfunction (ED). In clinical practice, however, many men do not continue long-term use of sildenafil for a variety of reasons; thus, 6 different aspects of optimizing treatment with sildenafil are ...

Viagra turns 15, but has it helped couples' sex lives?

4:56. The sexual potency pill revolutionized the treatment of erectile dysfunction and made billions worldwide. The little blue pill that's put the bounce back into the step of millions of men is ...

Serendipitous Story of Sildenafil: An Unexpected Oral Therapy for ...

Introduction. The introduction of sildenafil (Viagra [sildenafil citrate]; Pfizer Inc, New York, NY, USA) is broadly recognized as the achievement of the goal of a first-ever, government-approved, safe and effective oral treatment for erectile dysfunction (ED). 1 The development of Viagra was a serendipitous discovery and a major breakthrough in the treatment of ED.

Viagra's Journey to Blockbuster Patent and the Single Journal Article ...

This serendipitous discovery led to the drug's approval by the FDA in 1998 for the treatment of erectile dysfunction ... over 65 million men worldwide have been prescribed Viagra, with many more buying it over the counter since it was approved as a pharmacy medication in the UK in 2009. 3 Its commercial success mirrors its medical importance, ...

Achieving treatment optimization with sildenafil citrate (Viagra®) in ...

Since its approval in March 1998, the efficacy and safety of sildenafil citrate (Viagra; Pfizer, Inc, New York, NY) in treating erectile dysfunction (ED) have been evaluated in clinical trials totaling >11,000 patient-years. 1 Overall, >100 trials have been completed or are ongoing, involving >8000 men. 2 Efficacy of sildenafil, as evaluated using a global efficacy question (GEQ; improved ...