Is sildenafil safe in cirrhosis patients? - EurekAlert!

The result indicated that sildenafil do not induce any profound clinically relevant changes in splanchnic blood flow, oxygen consumption and HVPG in patients with cirrhosis. Phosphodiesterase type ...

Sildenafil does not influence hepatic venous pressure gradient in ...

Abstract. AIM: To investigate if sildenafil increases splanchnic blood flow and changes the hepatic venous pressure gradient (HVPG) in patients with cirrhosis. Phosphodiesterase type-5 inhibitors are valuable in the treatment of erectile dysfunction and pulmonary hypertension in patients with end-stage liver disease.

Viagra Disease Interactions - Drugs.com

PDE5 inhibitors (applies to Viagra) liver disease. Moderate Potential Hazard, High plausibility. Phosphodiesterase 5 (PDE-5) inhibitors are cleared predominantly by hepatic metabolism. The pharmacokinetic disposition of these agents has not been assessed in patients with severe hepatic impairment. No dosage modification is recommended for ...

Erectile dysfunction in cirrhosis is impacted by liver dysfunction ...

Flow chart diagram. 3.1. Erectile dysfunction and cirrhosis. Erectile dysfunction severity was significantly increasing throughout the CPS stages (P = .037, Table 1) and median IIEF‐5 scores were significantly decreasing with worsening of liver function (P = .038).The mean MELD was significantly higher in patients with ED (Figure 3).Also, the MELD increased significantly with severity of ED ...

Viagra has no effect on liver patients - Times of India

Viagra has no effect on liver patients. ANI / Nov 13, 2008, 10:55 IST. AA. Follow us. Sildenafil, a drug also sold as Viagra and known for treating erectile dysfunction (male impotence) and ...

Which Drugs Are Safe in Patients with Cirrhosis? - NEJM Journal Watch

Proton-pump inhibitors and, to a lesser degree, histamine-2 blockers have recently been associated with serious infections in patients with cirrhosis, so clinicians should limit their use to valid indications. Although most medications have not been sufficiently studied in patients with cirrhosis, most can be safely prescribed in this setting.

Can I take viagra safely and in what dose with liver cirrhosis??

Urologist: Dr. Tharun. Hi. The drug-Viagra is mainly metabolized in the liver and any disease which affects the liver can affect the activity of the drug Viagra. As in cirrhosis of liver the functional capacity of the liver is reduced and hence liver will take more time to break down the drug once it is consumed and so the drug will have more ...

Erectile dysfunction in patients with liver disease related to chronic ...

In respect to sexual dysfunction and liver disease, most studies have been conducted in patients with decompensated cirrhosis, those waiting liver transplants, or those with alcoholic liver cirrhosis.5,6,7 Patients with advanced liver disease often present with clinical features of hypogonadism, such as ED, infertility, decreased libido and ...

Viagra and Liver Conditions: Expert Answers to Your Questions

Doctor: Dr Ahmed. i can understand your concern. Well Vaigra does not have any liver related famous side effect. it is washed out from the body via kidney and feces. So Viagra 50 mg once a day is safe with early Cirrhosis. you quit drinking, that is another plus for you. I hope it helps.

Erectile dysfunction in patients with liver cirrhosis

Erectile dysfunction (ED) is defined as the inability to achieve or maintain an erection sufficient for satisfactory sexual performance [1]. The reported prevalence of ED ranges between 10% and 50% in the general population and is related to age, overall health status and emotional function [2,3]. Based on this high prevalence of ED and the progressive importance given to health related ...