Sildenafil (Viagra) for male erectile dysfunction: a meta-analysis of ...

An additional 277 men were given sildenafil at 5 mg or 200 mg. Details of trial design for the included studies is given in Additional File 2. Nine were parallel group and one had a crossover design, with fixed doses of sildenafil, or dose-optimised sildenafil, or both, and all had a placebo comparator group.

High dose sildenafil citrate as a salvage therapy for severe erectile ...

The objectives of this study were to evaluate the efficacy and tolerability of high dose sildenafil as a salvage therapy for patients refractory to the maximum recommended dose of sildenafil. ... 150 mg and 200 mg, respectively. 34/54 (63%) reported adverse effects with maximal dose sildenafil comprising headache (19), facial flushing (32 ...

Sildenafil in the treatment of erectile dysfunction: an overview of the ...

Long-term effectiveness of sildenafil was assessed in 3 open-label, flexible-dose (25 mg to 100 mg) studies. After 12 months of treatment (3 years in one study) or at the time of discontinuation, patients were asked if they were satisfied with the effect of the medication on erections, and if the treatment improved their ability to engage in ...

Pharmacokinetics of sildenafil after single oral doses in healthy male ...

Previous studies have shown that the pharmacokinetics of sildenafil and UK-103,320 were approximately dose proportional over the range of 1.25-200 mg, when administered orally [4, 10]. In the present dose-proportionality study, increases in C max and AUC were proportional to dose when consecutive dose increments were compared.

Viagra Online Pharmacy For Men

Viagra can last up to 5 hours or longer depending on your dosage, Viagra is a brand-name medication. It's also available in a generic form called sildenafil. Gastro-oesophageal reflux disease (acid reflux, symptoms include heartburn) Blood in urine (pee) Pain in the arms or legs.

Onset and duration of action of sildenafil for the treatment of ...

Sildenafil citrate (Viagra®, Pfizer) is a selective inhibitor of cGMP-specific phosphodiesterase type 5 (PDE5), ... -5 h; therefore, the drug's therapeutic response is expected to be sustained for at least 3 h following a dose of 100 mg. The two studies reported here were conducted to determine the time to onset (Study I) and duration of ...

Can I Take 200mg Of Sildenafil (Viagra)? - Everyone's MD

200mg of Sildenafil (Viagra) is the highest dose prescribed. Your doctor decides what treatment is best for you. Different dosages all work the same way and last about 4-6 hours, with 200mg being an effective dosage for men who don't respond to lower doses.

Pharmacokinetics of sildenafil after single oral doses in ... - PubMed

Aims: To determine the absolute bioavailability, dose proportionality and the effects of food on the pharmacokinetics of single oral doses of sildenafil citrate. Methods: Three open-label, randomized crossover studies were conducted in healthy male subjects. Absolute bioavailability was determined by comparing pharmacokinetic data after administration of single oral and intravenous 50-mg doses ...