Sildenafil and Cancer: The Potential Positives

In addition, there was initially some concern regarding biochemical recurrence of prostate cancer after radical prostatectomy and long-term PDE5 inhibitor use, however, more recent studies have ...

Erectile dysfunction drugs and skin cancer — should you worry?

1) This study does not show that Viagra causes skin cancer. Instead, it shows that in a large group of men, those who said they used Viagra ended up being diagnosed more often with melanoma than those who didn't use this drug. The study shows a connection, not a cause. 2). Even if Viagra does promote melanoma, the absolute increase is small.

The Potential Role of Sildenafil in Cancer Management through EPR ...

NO/sGC/cGMP pathway and sildenafil mechanism of action in erectile tissues and chemical structure of sildenafil. Nowadays, 11 PDE isoforms have been identified [].These isozymes share an aminoacidic homology superior to 65% and differ for their tissue distribution and affinity toward cAMP or cGMP; the latter is specifically degraded by PDE-5, -6, and -9 [4,5,6].

Erectile dysfunction and cancer: current perspective - PMC

Cancer diagnosis and its management lead to physical and emotional distress in patients. Sexual dysfunction is one of the common problems encountered in these patients which can occur due to direct or indirect pathways. Sexual dysfunction can be in the form of erectile dysfunction (ED) and ejaculatory dysfunction such as decreased or absent semen.

The Connection Between Viagra and Cancer - NutritionFacts.org

Men with advanced prostate cancer often have to get a radical prostatectomy, a surgery that can leave them both incontinent and impotent, which can reduce their quality of life. Therefore, a treatment concept called "penile rehabilitation" was introduced, where drugs like Viagra are given to counteract the side effects of the surgery.

Sildenafil (Viagra) sensitizes prostate cancer cells to doxorubicin ...

Sildenafil citrate (Viagra), a highly selective inhibitor of cGMP-specific phosphodiesterase type 5 (PDE5), is used clinically for treating erectile dysfunction (ED) and pulmonary hypertension. ... All forms of prostate cancer therapy cause significant risk of ED due to trauma sustained by the cavernosal nerves .

Viagra & Melanoma Skin Cancer - Symptoms & Treatment Options - Drugwatch

Skin cancer is the most common type of cancer in the U.S., most often affecting a person's head, face, neck, hands and arms. There are three major subgroups of skin cancer: basal cell cancer, squamous cell cancer, and melanoma. Basal cell cancer and squamous cell cancer are the most common forms of skin cancer, with melanoma being less common but the most serious of the three.

No Let Down: Viagra Does Not Increase Prostate Cancer Recurr ... - LWW

After you adjust for confounding factors, there is no relationship between phosphodiesterase type-5 inhibitors and prostate cancer recurrence." In the model using diagnostic variables, it appeared that as more pills were used, the less a risk of recurrence developed compared to men who were not using the phosphodiesterase type-5 products.

Viagra (Sildenafil) and Skin Cancer: How to Prevent Melanoma If You ...

The Link Between Viagra and Skin Cancer To understand the link between Viagra and skin cancer, you can start to see the link when you get into the mechanism of action of Viagra. This medication is very effective and has a limited number of side effects when a patient is healthy to make treatments very satisfying.