Vaginal sildenafil (Viagra): a preliminary report of a novel method to ...

Sildenafil citrate (Viagra), a type 5-specific phosphodiesterase inhibitor, augments the vasodilatory effects of NO by preventing the degradation of cGMP. In this preliminary report we describe the use of vaginal sildenafil to improve uterine artery blood flow and sonographic endometrial appearance in four patients with prior failed assisted ...

Benefit of vaginal sildenafil citrate in assisted reproduction therapy

In a preliminary report, Sher and Fisch described the use of vaginal sildenafil citrate to improve uterine artery blood flow and sonographic endometrial appearance in four patients with prior failed ART cycles. The potential side effects of sildenafil citrate may be minimized through the use of vaginal suppositories as a local rather than systemic delivery system.

"Effect of Vaginal Sildenafil on the Outcome of In Vitro Fertilization ...

The researchers proposed that Viagra, typically indicated to treat erectile dysfunction in men, would help women with a history of failed past fertility treatments by thickening their endometrial lining, which is the layer of tissue in the uterus where an embryo implants during pregnancy. ... Sher, Geoffrey, and Jeffrey D Fisch. "Vaginal ...

Effect of sildenafil citrate on treatment of infertility in women with ...

The effect of vaginal sildenafil citrate on uterine blood flow and endometrium in the infertile women. Akush Ginekol (Sofiia) 2013; 52: 26-30. [Google Scholar] 34. Sher G, Fisch JD. Effect of vaginal sildenafil on the outcome of in vitro fertilization (IVF) after multiple IVF failures attributed to poor endometrial development.