Viagra contraindicated in NAION patients - American Academy of ...

This is believed to be the largest case series published to date of NAION in patients who used the PDE5 inhibitor sildenafil (Viagra) for a prolonged period. Subjects included 10 NAION patients 38 to 70 years old in Saudi Arabia who used sildenafil at least two to three times per week during the weeks or months prior to the onset of vision loss.

Sildenafil citrate use and the incidence of nonarteritic anterior ...

Many of the risk factors for developing NAION also predict the occurrence of erectile dysfunction (ED), such as hypertension, diabetes, hyperlipidemia and smoking (7-9). Oral phosphodiesterase 5 inhibitors such as sildenafil citrate (Viagra ®, Pfizer Inc, New York, NY, USA) are the first-line treatment for ED in patients without ...

Erectile Dysfunction Drugs and Ischemic Optic Neuropathy: Is there a ...

Patients who are concerned about whether they might be at risk for NAION should have their ophthalmologists assess them for such possible risk factors as the small cup-to-disk ratio of the optic nerve, the presence of ischemic heart disease and other vascular risk factors like diabetes, hypertension, and hyperlipidemia. ... (viagra): a report ...

Sildenafil-associated nonarteritic anterior ischemic optic neuropathy

To describe the clinical features of five patients who developed nonarteritic anterior ischemic optic neuropathy (NAION) after ingestion of sildenafil citrate (Viagra; Pfizer Pharmaceuticals, New York, NY). ... Sildenafil citrate (Viagra, Pfizer Pharmaceuticals, New York, NY) is a selective phosphodiesterase 5 inhibitor and partial ...

Sequential, non-arteritic anterior ischemic optic neuropathy in ...

These authors proved that nocturnal arterial hypotension is the precipitating risk factor for NAION and Viagra can increase this nocturnal hypotension. Additionally Hayreh 3 showed that Viagra can be associated with an increase of norepinephrine levels that can produce vasoconstriction and ischemia in the optic nerve head.

Non-arteritic anterior ischaemic optic neuropathy and the treatment of ...

Aim: To determine the association between Viagra (sildenafil) and Cialis (tadalafil) and non-arteritic anterior ischaemic optic neuropathy (NAION). Methods: A retrospective matched case-control study was conducted. 38 cases of NAION in males were identified from an academic ophthalmology practice in Birmingham, Alabama, and matched (on age) to 38 controls without a history of NAION.

Non arteritic ischemic optic neuropathy (NAION): What is it?

NAION is an eye condition that causes sudden-onset, painless vision loss in one eye. Learn more. ... (Viagra) and the cancer medication interferon alpha, may contribute. Additionally, people with ...

Sildenafil-associated NAION - Ophthalmology

Pomeranz and colleagues' case series describing the occurrence of nonarteritic anterior ischemic optic neuropathy (NAION) after ingestion of sildenafil in five subjects invites speculation about the causative mechanism.1 Their thesis primarily emphasized the notions of disrupted autoregulation in the optic nerve head (ONH) or a toxic optic neuropathy from potentiation of nitric oxide by ...