Increasing Semen Volume - News-Medical.net

On abstaining for a long time, the sperm counts within the semen may increase, but the semen volume does not vary much from before. ... Viagra and its counterparts, Cialis, etc, do nothing for ...

Sildenafil's impact on male infertility: what has changed in ... - Nature

A large meta-analysis conducted in 2017 demonstrated no change in semen volume or concentration after PDE5 inhibitor administration, and observed a statistically significant increase in the ...

Sildenafil citrate and sperm function - American Journal of Obstetrics ...

There is currently no scientific basis to support the hypothesis that sildenafil citrate (Viagra; Pfizer, Inc, New York, NY) has any negative effects on sperm function. I regret that Andrade et al (Andrade JR, Traboulsi A, Hussain A, Dubin NH. In vitro effects of sildenafil and phentolamine, drugs used for erectile dysfunction, on human sperm motility. Am J Obstet Gynecol 2000;182:1093-5) did ...

Sildenafil Citrate Effects on Seminal Parameters in Male Par ...

The evidence reveals that sildenafil administration might have beneficial effects on many sperm parameters, such as sperm count, sperm motility, sperm morphology, semen volume, seminal fructose concentrations, and semen acidity.[12, 13, 14] It has been confirmed that the cyclic AMP, adenosine 3',5'-cyclic monophosphate (cAMP) concentrations ...

Sildenafil's impact on male infertility: what has changed in ... - PubMed

Sildenafil does not alter semen parameters, and, in fact, may positively affect semen parameters. Sildenafil is helpful for treating ED caused by the psychological stress of infertility treatments. Sildenafil has improved the treatment of ED and may have a benefit on semen parameters. This has aided in the management of male factor infertility ...

Effects of sildenafil (Viagra™) administration on seminal parameters ...

It has been demonstrated that human sperm cells contain as yet uncharacterized PDE isoforms which are different from PDE 1 and PDE 4, and that the in-vitro inhibition of sperm PDE 1 and PDE 4 isoenzymes by specific inhibitors stimulates acrosome reaction and sperm motility (Fisch et al., 1998). Also, it is known that after acute administration ...

The effects of sildenafil on human sperm function in healthy ... - PubMed

Aims: This double-blind, randomized, four-period, two-way crossover study was conducted to evaluate the acute effects of oral sildenafil (100-mg single dose) on sperm motility, count, density, morphology and vitality as well as ejaculate volume and viscosity in healthy male subjects. The concentrations of sildenafil and its primary circulating metabolite UK-103,320 were measured in ejaculate ...

Sildenafil citrate improves sperm motility but causes a premature ...

In both populations, sildenafil also caused a significant increase in the proportion of acrosome-reacted sperm-22.1% compared with 11.8% in the control group of the good quality fraction and 16.6% compared with 9.4% in the control group of the poorer quality fraction.

Full article: Concentration-dependent Sildenafil citrate (Viagra ...

Sildenafil Citrate (Viagra®, Pfizer) was the first oral agent approved by the FDA for the treatment of erectile dysfunction (ED), in 1998. ... Nanomolar range concentrations were reported to either induce an increase in sperm motility [Cuadra et al. Citation 2000], or to have no effect ... A small volume (50 μl) of the sperm sample (10 7 /ml ...