Viagra and Grapefruit Juice -- Not a Good Mix - TheBody

The men received a glass of grapefruit juice on an empty stomach and then one hour later another glass of grapefruit juice with Viagra 50 mg. Blood samples were collected over the next 24 hours.

Grapefruit Warning: It Can Interact with Common Medications - Healthline

Grapefruit and its close relatives can increase the blood levels of certain drugs and cause serious side effects. Affected drugs include some medications for blood pressure and heart rhythm, among ...

Effects of grapefruit juice on the pharmacokinetics of sildenafil

Conclusions: Grapefruit juice increases sildenafil bioavailability and tends to delay sildenafil absorption. Sildenafil pharmacokinetics may become less predictable with grapefruit juice. Although patients usually will not be endangered by concomitant use of grapefruit juice, it seems advisable to avoid this combination.

14 Medications to Avoid Mixing With Grapefruit - Verywell Health

Grapefruit can interact with many medications, potentially affecting the way they work or increasing side effects. Some of these drugs include statins, blood pressure medications, buspirone, certain opioids, and more. ... Viagra. By Ross Phan, PharmD, BCACP, BCGP, BCPS Ross is a writer for Verywell and has years of experience practicing ...

Drug Interactions with Grapefruit Juice - Drugs.com

Grapefruit is a nutritious fruit full of vitamin C, but many patients are concerned about the possibility of drug interactions. Maybe you've receive a pharmacy bottle with a warning label that recommends you avoid grapefruit or grapefruit juice while taking a certain medication. ... Viagra) simvastatin (Zocor) tadalafil (Adcirca, Cialis ...

Grapefruit-drug interactions - Wikipedia

The effect of grapefruit juice with regard to drug absorption was originally discovered in 1989 by a group led by pharmacologist David Bailey.Their first published clinical report on grapefruit drug interactions was in 1991. [9] The effect was first discovered accidentally in 1989, when a test of drug interactions with alcohol used grapefruit juice to hide the taste of the ethanol.

7 Medications That Don't Mix With Grapefruit and Its Juice

7. Viagra (Sildenafil) As early as 2002, four years after its initial 1998 release, researchers confirmed that grapefruit and the erectile dysfunction (ED) medication Viagra shouldn't mix ...