PDF Safe use of sildenafil in patients with coronary artery disease

Sildenafil in severe coronary artery disease Researchers at the University of Pennsylvania6 demonstrated that oral sildenafil had no direct adverse cardiovascular effects in 14 men with severe coronary artery disease. After the men took the drug, their systemic and pulmonary blood pressure decreased by a small but consis-tent amount (< 10%).

Use of sildenafil (Viagra) in patients with cardiovascular disease

A. Use of Viagra clearly contraindicated: 1. Concurrent use of nitrates (see Appendix A) B. Cardiovascular effects of Viagra may be potentially hazardous (use dependent on individual clinical assessment) ... In patients with known coronary artery disease whose antianginal medicines were stopped for study purposes , Drory et al compared the ...

Should the patient with coronary artery disease use sildenafil?

With the development of phosphodiesterase 5 inhibitors, the first of which was sildenafil (Viagra), an effective oral medication became available. The question of safety of these drugs, especially in patients with latent or overt coronary artery disease, is of concern.

Sildenafil in patients with cardiovascular disease

Endothelial dysfunction is an early abnormality that precedes by years the structural atherosclerotic blockage of blood vessels. Thus, patients who have coronary artery disease (CAD) risk factors but no angiographic or ultrasound evidence of atherosclerotic coronary stenosis may nonetheless have impaired endothelial function at the epicardial and microvascular levels.4 ED occurs in the setting ...

Sildenafil Is Safe and Effective in Men with Stable CAD | AAFP

Men in stable sexual relationships with confirmed erectile dysfunction who had stable coronary artery disease (CAD) were included. ... although vardenafil is specifically contraindicated for ...

Cardiovascular Effects of the 3 Phosphodiesterase-5 Inhibitors Approved ...

Currently, sildenafil (Viagra), vardenafil (Levitra), and tadalafil (Cialis) are on the market. These agents have been shown to be effective in a broad population of men with ED, including patients with vascular disease, coronary artery disease, hypertension, and ... Vardenafil is contraindicated in patients taking α-blockers. 19 When 10 or ...

Safe use of sildenafil in patients with coronary artery disease

Despite isolated reports of myocardial infarction and sudden cardiac death in men taking sildenafil for erectile dysfunction, clinical evidence shows the drug to be safe, effective, and well tolerated in most men with coronary artery disease. Nevertheless, caution is advised in specific instances.

Can Viagra Cause a Heart Attack? - Verywell Health

Coronary Artery Disease Atrial Fibrillation Heart Attack Heart Valve Disease Palpitations & Arrhythmias Chest Pain & Angina ... This article explores the safety of Viagra in people with heart disease as well as situations when Viagra may be contraindicated for use. It also offers tips on other ways to manage ED, including lifestyle changes and ...

Use of sildenafil (Viagra) in patients with cardiovascular disease:

ACC/AHA/ACP-ASIM guidelines for the management of patients with chronic stable angina11This document was approved by the American College of Cardiology Board of Trustees in March

SILDENAFIL (VIAGRA) AND THE HEART - PMC - PubMed Central (PMC)

Sexual dysfunction in men after the diagnosis of coronary artery disease or a myocardial infarction is common. 7 Most is due to the fear that the exertion of sexual activity will precipitate another myocardial infarction, but 10 to 15% of erectile dysfunction is due to organic causes. 8 In USA, approximately 5.5 million men take nitrates on a ...