Sildenafil in the treatment of pulmonary hypertension - PubMed

The therapy of pulmonary hypertension has evolved rapidly in the last 10 years from the use of non-selective vasodilators to drugs that specifically target pulmonary vasodilation, endothelial function, and vascular remodeling. Sildenafil is a phosphodiesterase type 5 inhibitor that has an expanding role in the treatment of pulmonary hypertension.

Sildenafil in the treatment of pulmonary hypertension

The therapy of pulmonary hypertension has evolved rapidly in the last 10 years from the use of non-selective vasodilators to drugs that specifically target pulmonary vasodilation, endothelial function, and vascular remodeling. Sildenafil is a phosphodiesterase type 5 inhibitor that has an expanding role in the treatment of pulmonary hypertension.

The Role of Sildenafil in Pulmonary Hypertension From Left ... - Chest

PURPOSE: Group 2 pulmonary hypertension or pulmonary hypertension from left heart disease (PH-LHD) is the most common type of pulmonary hypertension. Morbidity, mortality, and prognosis significantly worsen once pulmonary hypertension develops in patients with heart failure. The mainstay of treatment is to address the underlying heart disease and optimize treatment.