Viagra: How a Little Blue Pill Changed the World - Drugs.com

Viagra (sildenafil) was originally developed by Pfizer for high blood pressure and angina, but was found to be more effective at inducing erections. Learn how Viagra works, how to take it, and what are the risks and benefits of this ED treatment.

The Serendipitous Story of Sildenafil: An Unexpected Oral Therapy for ...

Introduction: The serendipitous discovery of sildenafil (Viagra [sildenafil citrate]) as a treatment for erectile dysfunction (ED) is one of the most fascinating drug development stories of our time. When sildenafil was approved by the U.S. Food and Drug Administration in 1998, it revolutionized the treatment protocol for men with ED, once considered a psychological issue or an inevitable part ...

The discovery and development of Viagra® (sildenafil citrate) - Springer

Sildenafil citrate is a selective inhibitor of phosphodiesterase type 5 (PDE5) that was first synthesised by Pfizer in 1989. It was originally developed for cardiovascular diseases, but later found to be effective for erectile dysfunction and pulmonary arterial hypertension.

Sildenafil: from angina to erectile dysfunction to pulmonary ...

Abstract. In less than 20 years, the first selective type 5 phosphodiesterase inhibitor, sildenafil, has evolved from a potential anti-angina drug to an on-demand oral treatment for erectile dysfunction (Viagra), and more recently to a new orally active treatment for pulmonary hypertension (Revatio).

Viagra: The little blue pill that could - CNN

Viagra was approved by the FDA on March 27, 1998 . British scientists working for Pfizer first created the drug in 1989. Since then three major competitors for Viagra have been approved.

What Is Viagra? - ScienceAlert

Viagra, the 'little blue pill' that is used by millions of men worldwide for erectile dysfunction, was actually discovered by accident. In the early 1990s, researchers working at the pharmaceutical company Pfizer were trying to invent a treatment for angina, ... as it was originally intended. ...

The Little Blue Pill: An Oral History of Viagra - Bloomberg

December 11, 2017 at 2:00 AM PST. Translate. Viagra's incredible run ended this morning with the release of a cheaper, generic version of the world's first impotence-fighting pill. And what a ...