Colchicine and Viagra drug interactions - eHealthMe

It is based on colchicine and sildenafil citrate (the active ingredients of Colchicine and Viagra, respectively), and Colchicine and Viagra (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Colchicine | Interactions | BNF | NICE

Colchicine has been reported to cause rhabdomyolysis when given with Pravastatin. Manufacturer advises caution or monitor. Severity: Severe. Evidence: Anecdotal. Ranolazine. Ranolazine is predicted to increase the exposure to Colchicine. Manufacturer advises avoid P-glycoprotein inhibitors or adjust Colchicine dose.

Colchicine Interactions Checker - Drugs.com

Colchicine Interactions. There are 291 drugs known to interact with colchicine, along with 7 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 118 are major, 168 are moderate, and 5 are minor.

The Top 7 Colchicine Interactions You Should Watch Out for - GoodRx

Azoles are a group of medications that treat fungal infections. Examples include yeast infections, thrush and athlete's foot.Examples of antifungals include ketoconazole, itraconazole (Sporanox), and fluconazole (Diflucan).. Azole antifungals block the enzyme that's responsible for metabolizing colchicine. Some azoles (like itraconazole and ketoconazole) also block a protein that ...

Life-threatening Colchicine Drug Interactions - Pharmacy Times

Colchicine is a known substrate for Pglycoprotein (PGP), a transmembrane protein that acts to eliminate drugs by expelling them into the bile, urine, and intestine and acting as a blood-brain barrier. The drugs reported to cause colchicine toxicity (eg, clarithromycin, erythromycin, cyclosporine, verapamil) are PGP inhibitors, and it is likely ...

Taking colchicine with other medicines and herbal supplements

Mixing colchicine with herbal remedies and supplements. There's not enough information to say that complementary medicines, herbal remedies and supplements are safe to take with colchicine. They're not tested in the same way as pharmacy and prescription medicines. They're generally not tested for the effect they have on other medicines.

Colchicine: Uses, Interactions, Mechanism of Action - DrugBank Online

Absorption. Colchicine is rapidly absorbed after oral administration from the gastrointestinal tract. 9 The bioavailability of colchicine is about 45%: 9,12 one study suggests that colchicine bioavailability is highly variable, ranging from 24 to 88%. 3 In healthy adults, the mean C max of 2.5 ng/mL (range 1.1 to 4.4 ng/mL) was achieved in one to two hours (range 0.5 to 3 hours) after a single ...

Colchicine: medicine used to treat gout - NHS

Colchicine Find out how colchicine treats inflammation and pain caused by gout and how to take it. About colchicine Who can and cannot take it How and when to take it Side effects Pregnancy, breastfeeding and fertility Taking it with other medicines and herbal supplements ...