The Role of Sildenafil in Treating Brain Injuries in Adults and ...

Mechanisms of action of sildenafil. Sildenafil Use in Neonates. The European Medicines Agency (EMA) approved sildenafil for children at low doses (<2 mg/kg/day) and, in 2014, the Federal Drug Administration (FDA) indicated that the benefit-risk profile of sildenafil (up to 6 mg/kg/day) was acceptable in children 1 year of age and older if closely monitored (Abman et al., 2013).

Sildenafil Use and Cigarette Smoking Associated with Intracerebral ...

Background. Intracerebral hemorrhage (ICH) is a serious condition characterized by bleeding within the brain tissue. Although the use of sildenafil, a vasodilator agent for erectile dysfunction, has been associated with rare cases of ICH, the combination of sildenafil usage and smoking as risk factors for ICH has not yet been reported.

Transient ischemic attack an stroke associated with sildenafil (Viagra ...

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Intraocular Hemorrhage due to use of Sildenafil in a Patient with ...

The current case was a diabetic patient with unilateral hyphema and vitreous hemorrhage, who used sildenafil. There is no definitive evidence to confirm that the hemorrhage in this case was caused by sildenafil itself. Nevertheless, it can be hypothesized that the bleeding was related to sildenafil due to the former described mechanisms.