Methadone and Viagra Interactions Checker - Drugs.com

Applies to: methadone and Viagra (sildenafil) Limited evidence suggests that use of narcotic medications like methadone may increase the effects of sildenafil. Rarely, there have been reports of prolonged erections lasting 2 to 5 hours. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives ...

Actual and Potential Drug Interactions Associated with Methadone

Mechanisms of Drug Interactions with Methadone. A drug interaction is defined as "the possibility that one drug may alter the intensity of pharmacological effects of another drug given concurrently" [3,4]. Drug interactions can either predominantly affect the pharmacokinetics or pharmacodynamics of the drug.

Sexual Dysfunction in Men Receiving Methadone Maintenance Treatment ...

Methadone patients scored significantly higher than controls on the 5-item rating ASEX scale, on CECA-Q and on Symptoms Check List 90 (SCL 90) scale. Testosterone plasma levels were significantly lower and PRL levels significantly higher in methadone patients with respect to the healthy control group. ASEX scores reflecting sexual dysfunction ...

Erectile dysfunction and quality of life in men receiving methadone or ...

ED complaints can be explored in male opioid users on ORT through a simple and quick self-assessment tool. ED may have important effects on emotional and social well-being, and may affect outcome. ... In our cohort, 598 patients (75.0%) were taking oral methadone (average daily dosage: 58.0 ± 47.3 mg, median: 50, range: 2-350), and 199 ...

Combining Methadone With Other Opioids - Medscape

The duration of analgesia is approximately 3-6 hours at the start of therapy and extends to 8-12 hours with repeated dosing. Plasma levels of methadone generally stabilize within 5-7 days due to ...